About
Colin M. Skinner, PhD
PhD, Bioengineering, UC Berkeley
I solve complex problems with software, machine learning, and AI agents.
My background spans software engineering, machine learning, and computational biology. I earned my PhD in Bioengineering from UC Berkeley, with a Designated Emphasis in Computational Biology, where my research focused on machine learning methods for DNA methylation clocks and aging biology.
My recent work has focused on AI systems and developer infrastructure, including multi-agent orchestration, research platforms, retrieval systems, and tools for building reliable AI workflows. I'm especially interested in problems at the intersection of machine learning and software engineering.
Resume
Education and selected work
A short sketch. The full record is on LinkedIn.
2025
PhD, Bioengineering (designated emphasis in Computational Biology)
University of California, Berkeley
Dissertation on hypothesis-driven training for DNA methylation clocks and feature rectification for linear-model coherence to detect inflammaging.
Now
Stephen King True Value
stephenkingtruevalue.com
A free community resource for Stephen King collectors — real-market valuations, identification points, and a place to share knowledge.
Dissertation
PhD, Bioengineering, UC Berkeley, 2025
Hypothesis-Driven Training for DNA Methylation Clocks and Feature Rectification for Linear Model Coherence to Detect Inflammaging
Research
Publications
Works listed on ORCID 0000-0002-6335-4493. Preprints are labeled as such.
ORCID 0000-0002-6335-4493 (opens in a new tab)
2024 · bioRxiv · preprint
DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging (opens in a new tab)doi:10.1101/2024.10.09.617512
2022 · Nature Protocols
Small-animal blood exchange is an emerging approach for systemic aging research (opens in a new tab)doi:10.1038/s41596-022-00731-5
2021 · GeroScience
Plasma dilution improves cognition and attenuates neuroinflammation in old mice (opens in a new tab)doi:10.1007/s11357-020-00297-8
2020 · Skeletal Muscle
Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation (opens in a new tab)doi:10.1186/s13395-020-0222-1
2020 · Aging
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (opens in a new tab)doi:10.18632/aging.103418
2017 · Nature Biomedical Engineering
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair (opens in a new tab)doi:10.1038/s41551-017-0137-2
Now
Shipping this site as a small product and running Stephen King True Value as a free collector resource. Open to conversations about product, platform, and research-adjacent engineering roles.
Interests
Computational biology, DNA methylation clocks, and aging research — plus software that treats data products as something a person can actually use.
Agents and tools, local-first software, and products that admit they can fail.
Contact
LinkedIn and X are the fastest public ways to reach me.